St. Louis 61 Memphis 54 - Kwamain Mitchell scored 22 points off the bench for the Billikens as St. Louis downed Memphis in a mild 9-8 upset. St. Louis held Memphis to 39% shooting and had a five rebound edge on the boards. Mitchell was 9-for-14, making 4 of 7 three-pointers.
Lehigh 75 Duke 70 - Lehigh's CJ McCollum threw up 22 shots, made nine of them, including two three pointers and was 10-for-16 from the foul line for a game high 30 points as the Mountain Hawks upset #2 seed Duke. It was the third major upset of the day, after #2 Missouri was knocked out of the West region by Norfolk State and Michigan, the #4 seed in the Midwest went down to Ohio.
Ohio 65 Michigan 60 - Ohio took it to the Wolverines early and late, taking an early lead and maintaining it throughout. The Bobcats shot 51% from the field, while Michigan registered just 41% shooting. Ohio's DJ Cooper had the whole game on, leading all scorers with 21 points on 7-for-11 shooting (3-6 on threes) and four of five from the line with five assists and a couple of rebounds.
Purdue 72 St. Mary's 69 - The Boilermakers led the entire game, except for a few brief seconds late in the game when St. Mary's took a 69-68 lead with 44 seconds left. But Purdue scored the final four points of the contest to seal the win and move to the next round. Purdue guard Terone Johnson had a game high 23 points on 10 of 14 shooting with four rebounds and five assists.